In this issue of Neuroimaging Clinics, guest editors Drs. Joseph Gemmete and Zachary Wilseck bring their considerable expertise to the topic of Advanced Imaging in Ischemic and Hemorrhagic Stroke. Top experts in the field discuss metabolic imaging such as PET, in vivo O17 MRS imaging, quantitative sodium MR imaging, pharmacological MRI (pHMRI), dual-energy CT, vessel wall imaging, and more. Contains 11 relevant, practice-oriented topics including CT/CTA/perfusion in acute ischemic stroke/vasospasm; MRI/MRA/perfusion in acute ischemic stroke and vasospasm; MR imaging of cerebral aneurysmal wall for rupture risk; dual-energy CT in imaging of acute ischemic and hemorrhagic stroke; metabolic imaging of acute ischemic stroke (PET, spectroscopy, O17 imaging, sodium imaging, PH imaging); and more. Provides in-depth clinical reviews on advanced imaging in ischemic and hemorrhagic stroke, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.