Systematic Review and Meta-Analysis: Stepwise Approach for Medical and Biomedical Researchers presents a step-by-step approach to develop systematic reviews and meta-analysis for biomedical and medical research. Systematic reviews are the highest quality evidence in medical research, providing an answer to a specific question, and they can be developed in the form of comprehensive literature search, critical appraisal, and synthesis of the evidence. Systematic reviews and meta-analysis are key elements of evidence-based medicine by summarizing the results of previous studies with the use of specific and reliable methods. Initially, systematic review and meta-analysis were exclusive to clinical trials, however systematic reviews of observational and diagnostic studies have expanded, making it essential for members of the field to master those techniques. This practical reference is a valuable resource for biostaticians, researchers, students, and members of medical and biomedical fields who need to understand more about systematic reviews and meta-analysis in their research work.