This book has been written with the intention to fill two big gaps in the reliability and risk literature: the risk-based reliability analysis as a powerful alternative to the traditional reliability analysis and the generic principles for reducing technical risk. An important theme in the book is the generic principles and techniques for reducing technical risk. These have been classified into three major categories: preventive (reducing the likelihood of failure), protective (reducing the consequences from failure) and dual (reducing both, the likelihood and the consequences from failure). Many of these principles (for example: avoiding clustering of events, deliberately introducing weak links, reducing sensitivity, introducing changes with opposite sign, etc.) are discussed in the reliability literature for the first time. Significant space has been allocated to component reliability. In the last chapter of the book, several applications are discussed of a powerful equation which constitutes the core of a new theory of locally initiated component failure by flaws whose number is a random variable.