
Pharmaceutical Biocatalysis
2 712 kr
2 712 kr
Ma., 28 april - ma., 5 mai
Sikker betaling
14 dagers åpent kjøp
Selges og leveres av
Adlibris
Produktbeskrivelse
This volume of Pharmaceutical Biocatalysis starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types; human DOPA decarboxylase, related to Parkinson's disease and aromatic amino acid decarboxylase deficiency; and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. An additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors targeting receptor tyrosine kinases in cancer, ß-Lactams and related compounds as antibacterials, non-vitamin K oral anticoagulants for the treatment of thromboembolic diseases, and the molecular mechanisms for statin pleiotropy and its clinical relevance in cardiovascular diseases. The last chapter is a review of lysosomal storage disorders with an overview of approved drugs for treating these disorders by enzyme replacement therapy.
Artikkel nr.
569f85af-fa7d-4902-af73-e3a907698ed7
Pharmaceutical Biocatalysis
2 712 kr
2 712 kr
Ma., 28 april - ma., 5 mai
Sikker betaling
14 dagers åpent kjøp
Selges og leveres av
Adlibris
Lignende toppselgere

Øreputer for Bose QuietComfort - QC35/QC25/QC15/AE2 Hodetelefoner Svart
99 kr

Anti-snork Bånd / Magnetiske Plaster - Stopper snorking
149 kr

Universallader for Garmin klokker Svart
89 kr

4-Pak - Tesla Senterkopper - Bil Svart/silver
129 kr

Luftrenseenhet - Renser / Saniterer luften - 20,000 mg/h
599 kr

RCA til HDMI Converter 1080p - Adapter
139 kr

4-Pak - Volkswagen VW Senterkopper - Bil 65 mm
129 kr

Hundetrimmer / Potetrimmer - Trimmer for Poter
199 kr

Trådløs CarPlay-adapter 2025
449 kr
Tidligere laveste pris:
459 kr

SIGNS STEELBOOK
379 kr
Anbefalinger til dig

4-Pak - BMW Senterkopper - Bil 68 mm
129 kr

Plenlufter - Piggsko for å lufte plenen
269 kr

INF Øreputer for Bose QC35 I/II, QC25, QC15, QC 2 AE 2, AE 2i, AE 2w, SoundTrue, SoundLink
99 kr

INF TYPE-C Dual SD/TF-kortleser for rask dataoverføring 0
99 kr
Tidligere laveste pris:
107 kr

2-Pak - Lader for iPhone - Hurtiglader - Adapter + Kabel 20W USB-C
199 kr

3-Pak - Fidget Spinners med Sugekopp for Barn
179 kr

INF Filter for MSPA oppblåsbare bassenger FD2089 4-pakning
299 kr

INF SCART til HDMI-omformer 1080p
141 kr

INF Hjulmutterhette med fjerningsverktøy, 20-pak 21 mm
95 kr

Digital vekt - lommevekt, smykkevekt 0,01 - 200g
119 kr