This issue of Otolaryngologic Clinics, Guest Edited by Drs. Adrien A. Eshraghi and Fred F. Telischi, is devoted to Otosclerosis and Stapes Surgery. Articles in this outstanding issue include: Otosclerosis: Temporal Bone Pathology; Otosclerosis: From Genetics to Molecular Biology; Otosclerosis and Stapes Surgery, Historical Aspects; Clinical Evaluation of the Patient with Otosclerosis; Impact of Imaging in the Management of Otosclerosis; Medical Management of Otosclerosis; Otosclerosis: Audiological Evaluation and Hearing Aids; Stapes Surgery: Stapedectomy Versus Stapedotomy; Use of Lasers in Otosclerosis Surgery; The Stapes Prosthesis: Past, Present and Future; Endoscopic Stapes Surgery; Advanced Otosclerosis and Cochlear Implantation; Special Anatomical Considerations in Otosclerosis Surgery; Revision Surgery for Otosclerosis; Complication in Otosclerosis Surgery; The Potential of Robotic Surgery for Otosclerosis; and Controversies in Otosclerosis.