This publication contains 36 papers presented at four symposia during the Thirty-first COSPAR Scientific Assembly held in Birmingham, UK during 1996. Papers reflect the following symposia themes: life science support system studies; production, processing and waste recycling in a CELSS (Controlled Ecological Life Support System); biological effects of closure and recycling in a CELSS; nutrition and productivity for bioregenerative life support; integration of bioregenerative and physical/chemical processes for space life support systems. Findings presented in this volume will be a valuable resource for CELSS researchers for many years to come.