Signs of science? The science of signs? Or neither, or both. How about the sleep depriving thought of eternity when you turn off the lights at night. Of the ever reaching deepness of space, black holes and the creation of photons in the core of the sun. How about when you get lost in thought, staring at your thumb, thinking about how the cells in your skin work and work and work, divide and fall off. The molecules they are made of. The vanishing weight of the atoms. How did the insects develop wings? What is the purpose of the flick-flack of the Rechenbergi spider, the tiny squeak of the desert rain frog, the Higgs boson? And what is dark energy anyway? The history of the natural sciences is filled with wonder, with horror and gore, with idealism and the search for truth, but above all curiosity. These questions were the basis for this issue of CBA. Full speed ahead, towards the event horizon of CBA!