As the National Quality Advisor and Chair of the AGAI Clinical Practice and Quality Management Committee, Dr. Allen, along with Dr. DeLegge, have created a very insightful list of topics to educate gastroenterologists about how to adapt to health care reform. The issue addresses the impact in both private practices and academic medical centers. Specific issues discussed include Gastroenterologists and Accountable Care Organizations; Health Information Technology and the Gastroenterologist; Transitioning from Fellowship to Practice 2012; Going Big in Private Practice; Clinical Service Line Management; The Impact of Health Reform on GI Reimbursement; The Impact of Health Care Reform on Innovation and New Technology; Industry and Gastroenterology: A New World; and Demonstrating Value: Registries and Beyond.