Advances in Immunology, Volume 143, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on the design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, gender bias, fungi, fibrinolysis and allergic airway inflammation, updating and interpreting airway epithelial cell reprogramming in bronchial asthma, the link(s) of sensing to the immune response, and the regulatory role of the autonomic system.